Under the terms of the deal, Lotto benchwear will be work by every manager and assistant manager in the three divisions, whilst Lotto will also become sponsors of the Golden Boot and Golden Glove awards for the top goalscorer and goalkeeper.
The decision to appoint Lotto came following a tender process in which nine kit suppliers were considered.
Announcing the new deal, Northern Premier League chairman Mark Harris revealed that the new deal offered significantly better terms to the previous deal with Adidas.
"We are delighted to be working with Lotto, whose presentation demonstrated that they are determined to make their mark in the non-league game.
In addition to the new benchwear that will be worn by every member club, and the financial contribution that will further benefit all clubs, Lotto are already working closely with our new league sponsors to encourage as many of our clubs as possible to sign up with Lotto for 2010/11," he said.
Lotto Teamwear UK Director Mark Ragan said: “Lotto takes great pride in being the technical kit supplier of the Northern Premier League, and is excited about the prospects of working with the many chairmen and staff that make an incredibly well run and exciting competition.”